Vizslas' mode of inheritance

This is the main focus of the research underway by the Canine Epilepsy Research Consortium. Some of your questions may not have clear answers at this time, but ask them anyway!

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Tierah
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Joined: Fri Jan 11, 2002 1:01 am

Vizslas' mode of inheritance

Post by Tierah » Thu Dec 19, 2002 5:50 pm

It has been nearly a year since I have asked - do you have any new news on the mode of inheritance of Epilepsy in Vizslas?

Ned Patterson DVM
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Location: University of Minnesota Veterinary College
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Post by Ned Patterson DVM » Fri Dec 20, 2002 11:02 am

We presented an abstract a the Annual Meeting of the American College of Veterinary Internal Medicine last summer about the inheritance and clinical characteristics of epilepsy in Vizlsas. Our analysis indicates that the way epilepsy segregates (is passed on in families) is consistent with one gene autosomal recessive inheritance but we cannot be totally sure at this point that there could a few genes involved. A paper with these details has been accepted by a major veterinary journal and once it is published we will pass on the specifics.

We are in the midst of looking for genetic markers linked to (associated with) epilepsy in Vizslas, and we presented the initial findings of this at a human genetics meeting in October. Once we find a confirmed, linked marker we will be able to be much more sure about the mode of inheritance. This could happen in a few months or a few years depending on a number of factors but we are confidant that it will happen. A linked set of markers can be used as a screening test to help with breeding decisions, and will eventually lead to the finding of the defective gene or genes.

Vizsla
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Joined: Mon Sep 22, 2003 3:53 pm

Vizsla Mode of Inheritance

Post by Vizsla » Mon Sep 22, 2003 3:55 pm

Have you made any leaps forward in isolating the Vizsla Epi gene? I have read you article posted to the website.

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