This is the main focus of the research underway by the Canine Epilepsy Research Consortium. Some of your questions may not have clear answers at this time, but ask them anyway!
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I was, unfortunately, not able to attend the update at the National last June in Lancaster, PA. I have heard some of the progress from attendees, but would love to see it straight from the horses mouth as it were. As I understand, there was some real progress to report.